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Article

Is tissue-plasminogen activator gene polymorphism a risk factor for venous thromboembolism in every population?

Journal of thrombosis and thrombolysis - 1 Feb 2005

Oguzulgen I Kivilcim, Ekim Numan, Erkekol Ferda Oner, Altinok Buket, Akar Nejat

Abstract excerpt

BACKGROUND: Tissue-plasminogen activator is a key protein of fibrinolytic system. In recent years the relation between t-PA, its genetic polymorphisms and arterial or venous thrombosis were investigated in different populations. The aim of this study is to investigate the role of t-PA gene polymorphism in Turkish venous thromboembolism (VTE) patients. METHODS: A case-control study was performed. We investigated...

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PMID: 15976969
DOI: 10.1007/s11239-005-0941-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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