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Article

Mutation screening of BMP4, BMP7, HOXA4 and HOXB6 genes in Chinese patients with hypospadias.

European journal of human genetics : EJHG - 1 Jan 2007

Chen Taiji, Li Qiang, Xu Jiajie, Ding Keyue, Wang Yanping, Wang Weiqiu, Li Senkai, Shen Yan

Abstract excerpt

Hypospadias, one of the most common congenital abnormalities of the male external genitalia with elusive etiology, are caused by a defect in the normal development of the urethra, foreskin and ventral aspect of the penis. Evidences indicate that BMP4 and BMP7, two of those major factors in a signaling cascade involved in controlling the embryonic urethral development, play central roles in the normal development...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17003840
DOI: 10.1038/sj.ejhg.5201722

Genes

BMP4
BMP7
HOXA4
HOXB6

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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