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Article

A novel duplication downstream of BMP2 in a Chinese family with Brachydactyly type A2 (BDA2).

Gene - 5 Feb 2018

Wang Wen-Bo, Jia Ya-Chao, Zhang Zeng, Xu Jia, Zuo Rong-Tai, Kang Qing-Lin

Abstract excerpt

BACKGROUND: Brachydactyly type A2 (BDA2) is an autosomal dominant disease characterized by the deformation of the middle phalanx of the second fingers and toes. It has been reported to be associated with three genes regulating the osteogenesis, including BMPR1B, GDF5 and BMP2. MATERIALS AND METHODS: 10 BDA2 patients and 7 unaffected individuals in a Chinese family were identified through clinical signs and...

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Source

Identifiers

PMID: 29129813
DOI: 10.1016/j.gene.2017.11.024

Genes

BMP2
GDF5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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