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Article

Mutation analysis of five candidate genes in Chinese patients with hypospadias.

European journal of human genetics : EJHG - 1 Sept 2004

Wang Yanping, Li Qiang, Xu Jiajie, Liu Qingjie, Wang Weiqiu, Lin Yi, Ma Fen, Chen Taiji, Li Senkai, Shen Yan

Abstract excerpt

Hypospadias is the displacement of the urethral meatus from the tip of the glans to the ventral side of the phallus. During fetal development, SRY, SOX9, WT1, SRD5A2 and AR are important at different stages in the differentiation and development of the male genital system. Mutations in these genes impair masculinization and may be associated with hypospadias. In order to explore these possibilities, we employed...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 15266301
DOI: 10.1038/sj.ejhg.5201232

Genes

SOX9
SRY

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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