Article
Association study between the CX3CR1 gene and asthma.
Genes and immunity - 1 Dec 2006
Tremblay K, Lemire M, Provost V, Pastinen T, Renaud Y, Sandford A J, Laviolette M, Hudson T J, Laprise C
Abstract excerpt
CX3CR1, a fractalkine receptor, mediates cell-adhesive and migratory functions in inflammation. Based on CX3CR1 expression observed in bronchial tissues of asthmatic subjects, we hypothesized that genetic variation at this locus may affect susceptibility to asthma. We carried out an association study and a haplotypic analysis with selected polymorphisms of the CX3CR1 in a familial asthmatic sample from a founder...
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