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Article

Generation of activin receptor type IIB isoform-specific hypomorphic alleles.

Genesis (New York, N.Y. : 2000) - 1 Oct 2006

Lee Young Jae, Hong Kwon-Ho, Yun Jihye, Oh S Paul

Abstract excerpt

Activin receptor type IIB (Acvr2b) mediates multiple signals for transforming growth factor-beta (TGF-beta) family members, including Activin, Nodal, Bmp7, Gdf1, Gdf3, Myostatin (Gdf8), and Gdf11. Mouse Acvr2b gene generates four transcriptional isoforms (Acvr2b(1-4)) via alternative splicing of two sequence domains located at the juxtaposition of the transmembrane domain. To investigate whether these splicing...

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Identifiers

PMID: 16991118
DOI: 10.1002/dvg.20238

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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