Article
[Analysis of prognostic value of TP53 gene mutations in non-small cell lung cancer].
Pneumonologia i alergologia polska - 1 Jan 2005
Szymanowska Amelia, Jassem Ewa, Dziadziuszko Rafał, Skrzypski Marcin, Kobierska-Gulida Grazyna, Holm Karolina, Borg Ake, Rzyman Witold, Limon Janusz, Jassem Jacek
Abstract excerpt
The aim of this study was to assess the frequency and prognostic value of TP53 gene somatic mutations in non-small cell lung cancer. The study group included 240 NSCLC patients who underwent pulmonary resection at the Department of Thoracic Surgery, Medical University of Gdańsk. Tumour samples were evaluated for the presence of TP53 gene mutations in exons 5-8. In 157 cases SSCP method was used as a screening...
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