Article
Genome-wide scan for linkage to schizophrenia in a Spanish-origin cohort from Costa Rica.
American journal of medical genetics - 8 Jul 2002
DeLisi Lynn E, Mesen Andrea, Rodriguez Carlos, Bertheau Arturo, LaPrade Beatrice, Llach Michelle, Riondet Silvina, Razi Kamran, Relja Margaret, Byerley William, Sherrington Robin
Abstract excerpt
Genetic isolates have been useful cohorts in which to search for genes underlying disorders of unknown pathology. One such cohort is thought to exist in the Central Valley of Costa Rica surrounding the city of San Jose. Previous investigators identified a rare dominant gene for hereditary deafness in this population, and a suggestive linkage of severe bipolar psychosis has been reported in another study....
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