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Article

The conserved ASTN2/BRINP1 locus at 9q33.1-33.2 is associated with major psychiatric disorders in a large pedigree from Southern Spain.

Scientific reports - 15 Jul 2021

Pol-Fuster Josep, Cañellas Francesca, Ruiz-Guerra Laura, Medina-Dols Aina, Bisbal-Carrió Bàrbara, Ortega-Vila Bernat, Llinàs Jaume, Hernandez-Rodriguez Jessica, Lladó Jerònia, Olmos Gabriel, Strauch Konstantin, Heine-Suñer Damià, Vives-Bauzà Cristòfol, Flaquer Antònia

Abstract excerpt

We investigated the genetic causes of major mental disorders (MMDs) including schizophrenia, bipolar disorder I, major depressive disorder and attention deficit hyperactive disorder, in a large family pedigree from Alpujarras, South of Spain, a region with high prevalence of psychotic disorders. We applied a systematic genomic approach based on karyotyping (n = 4), genotyping by genome-wide SNP array (n = 34) and...

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PMID: 34267256
DOI: 10.1038/s41598-021-93555-4
PMCID: PMC8282839

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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