Article
OMA-AML-1: a leukemic myeloid cell line with CD34+ progenitor and CD15+ spontaneously differentiating cell compartments.
Blood - 15 Aug 1992
Pirruccello S J, Jackson J D, Lang M S, DeBoer J, Mann S, Crouse D, Vaughan W P, Dicke K A, Sharp J G
Abstract excerpt
OMA-AML-1 was established from a patient with acute myelomonocytic (M4) leukemia at fifth relapse when blasts were greater than 85% CD34+, CD15-. Leukemic cells were established in suspension culture and independently grown as subcutaneous tumors in SCID mice. Cells growing in suspension culture underwent differentiation by phenotypic and morphologic criteria. In contrast, cells grown as subcutaneous solid tumors...
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