Article
OMA-AML-1: a leukemic myeloid cell line with CD34+ progenitor and CD15+ spontaneously differentiating cell compartments.
Blood - 15 Aug 1992
Pirruccello S J, Jackson J D, Lang M S, DeBoer J, Mann S, Crouse D, Vaughan W P, Dicke K A, Sharp J G
Abstract excerpt
OMA-AML-1 was established from a patient with acute myelomonocytic (M4) leukemia at fifth relapse when blasts were greater than 85% CD34+, CD15-. Leukemic cells were established in suspension culture and independently grown as subcutaneous tumors in SCID mice. Cells growing in suspension culture...
Topics
- Animals
- Antigens, CD
- Antigens, CD34
- Cell Differentiation
- Granulocyte-Macrophage Colony-Stimulating Factor
- Humans
- Interleukin-3
- Interleukin-6
- Leukemia, Myelomonocytic, Acute
- Lewis X Antigen
- Mice
- Mice, Nude
- Mice, SCID
- Neoplasm Transplantation
- Phenotype
- Stem Cells
- Tumor Cells, Cultured