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Article

Establishment and characterization of a granulocyte-macrophage colony-stimulating factor-dependent human myeloid cell line.

Blood - 1 Aug 1990

Oez S, Tittelbach H, Fahsold R, Schaetzl R, Bührer C, Atzpodien J, Kalden J R

Abstract excerpt

A new human myeloid cell line has been established recently from the bone marrow cells of a patient with chronic myelogenous leukemia in blast crisis. The active proliferation and survival of the cells in RPMI 1640 medium containing fetal calf serum are clearly dependent on the presence of either natural or recombinant human granulocyte-macrophage colony-stimulating factor (rhGM-CSF). Despite permanent culturing...

Topics

Blast Crisis
Blotting, Southern
Bone Marrow
Cell Line
Colony-Stimulating Factors
DNA
Female
Granulocyte-Macrophage Colony-Stimulating Factor
Growth Substances
Humans
Karyotyping

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Leukemia, Myelogenous, Chronic, BCR-ABL Positive

Middle Aged

Phenotype

Source

Identifiers

PMID: 2198961

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2198961-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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