Monocyte function in IDDM patients and healthy individuals.

doi:10.1111/j.1365-3083.1990.tb02924.x

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Article

Monocyte function in IDDM patients and healthy individuals.

Scandinavian journal of immunology - 1 Sept 1990

Mølvig J, Pociot F, Baek L, Worsaae H, Dall Wogensen L, Christensen P, Staub-Nielsen L, Mandrup-Poulsen T, Manogue K, Nerup J

Abstract excerpt

Interleukin 1 beta (IL-1 beta) and tumour necrosis factor alpha (TNF-alpha) may be pathogenetically important in insulin-dependent diabetes mellitus (IDDM), which is associated with genes of the HLA region. Since a regulatory role of HLA region genes on monokine production may exist, we looked for an association between the monokine and prostaglandin E2 (PGE2) responses of monocytes (Mo) from 20 healthy males...

Topics

Adolescent
Adult
Alleles
Diabetes Mellitus, Type 1
Dinoprostone
Dose-Response Relationship, Drug
HLA-DR Antigens
Humans
Immunoblotting
Interferons
Interleukin-1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Lipopolysaccharides

Male

Middle Aged

Monocytes

Phenotype

Polymorphism, Restriction Fragment Length

Reference Values

Source

Open in PubMed

Identifiers

PMID: 1698309
DOI: 10.1111/j.1365-3083.1990.tb02924.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1698309-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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