Electrostatic interactions in the channel cavity as an important determinant of potassium channel selectivity.

Abstract excerpt

Potassium channels are membrane proteins that allow the passage of potassium ions at near diffusion rates while severely limiting the flux of the slightly smaller sodium ions. Although studies thus far have focused on the narrowest part of the channel, known as the selectivity filter, channels are long pores with multiple ions that traverse the selectivity filter, the water-filled central cavity, and the rest of...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Amino Acids
• Share to Cell Membrane Permeability