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Article

Identification of susceptibility loci for skin disease in a murine psoriasis model.

Journal of immunology (Baltimore, Md. : 1950) - 1 Oct 2006

Kess Daniel, Lindqvist Anna-Karin B, Peters Thorsten, Wang Honglin, Zamek Jan, Nischt Roswitha, Broman Karl W, Blakytny Robert, Krieg Thomas, Holmdahl Rikard, Scharffetter-Kochanek Karin

Abstract excerpt

Psoriasis is a frequently occurring inflammatory skin disease characterized by thickened erythematous skin that is covered with silvery scales. It is a complex genetic disease with both heritable and environmental factors contributing to onset and severity. The CD18 hypomorphic PL/J mouse reveals reduced expression of the common chain of beta(2) integrins (CD11/CD18) and spontaneously develops a skin disease that...

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Identifiers

PMID: 16982899
DOI: 10.4049/jimmunol.177.7.4612

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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