Article
Psoriasis and other complex trait dermatoses: from Loci to functional pathways.
The Journal of investigative dermatology - 1 Mar 2012
Capon Francesca, Burden A David, Trembath Richard C, Barker Jonathan N
Abstract excerpt
Driven by advances in molecular genetic technologies and statistical analysis methodologies, there have been huge strides taken in dissecting the complex genetic basis of many inflammatory dermatoses. One example is psoriasis, for which application of classical linkage analysis and genome-wide association investigation has identified genetic loci of major and minor effect. Although most loci independently have...
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