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Article

A 9-centimorgan interval of chromosome 10 controls the T cell-dependent psoriasiform skin disease and arthritis in a murine psoriasis model.

Journal of immunology (Baltimore, Md. : 1950) - 15 Apr 2008

Wang Honglin, Kess Daniel, Lindqvist Anna-Karin B, Peters Thorsten, Sindrilaru Anca, Wlaschek Meinhard, Blakytny Robert, Holmdahl Rikard, Scharffetter-Kochanek Karin

Abstract excerpt

Psoriasis is a complex genetic disease of unresolved pathogenesis with both heritable and environmental factors contributing to onset and severity. In addition to a disfiguring skin inflammation, approximately 10-40% of psoriasis patients suffer from destructive joint involvement. Previously, we reported that the CD18 hypomorphic PL/J mouse carrying a mutation resulting in reduced expression of the common chain...

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PMID: 18390736
DOI: 10.4049/jimmunol.180.8.5520

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TNF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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