Article
The genetics of psoriasis, psoriatic arthritis and atopic dermatitis.
Human molecular genetics - 1 Apr 2004
Bowcock Anne M, Cookson William O C M
Abstract excerpt
Psoriasis and atopic dermatitis are chronic and relapsing inflammatory diseases of the skin associated with various immunologic abnormalities. Approximately 30% of psoriasis patients also have joint involvement, indicative of psoriatic arthritis. Genes and environment play a key role in the pathogenesis of these diseases. Genome-wide linkage scans have identified multiple loci linked to each disease and revealed...
Topics
- Arthritis, Psoriatic
- Chromosomes, Human
- Dermatitis, Atopic
- Environmental Exposure
- Genes, Overlapping
- Genetic Diseases, Inborn
- Humans
- Polymorphism, Single Nucleotide
- Psoriasis
- Skin
