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Article

A genome-wide map of aberrantly expressed chromosomal islands in colorectal cancer.

1 Jan 2006

Abstract excerpt

BACKGROUND: Cancer development is accompanied by genetic phenomena like deletion and amplification of chromosome parts or alterations of chromatin structure. It is expected that these mechanisms have a strong effect on regional gene expression. RESULTS: We investigated genome-wide gene expression in colorectal carcinoma (CRC) and normal epithelial tissues from 25 patients using oligonucleotide arrays. This...

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PMID: 16982006
DOI: 10.1186/1476-4598-5-37

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