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Article

Candidate driver genes in focal chromosomal aberrations of stage II colon cancer

23 Apr 2010

Abstract excerpt

Chromosomal instable colorectal cancer is marked by specific large chromosomal copy number aberrations. Recently, focal aberrations of 3 Mb or smaller have been identified as a common phenomenon in cancer. Inherent to their limited size, these aberrations harbour one or few genes. The aim of this study was to identify recurrent focal chromosomal aberrations and their candidate driver genes in a well-defined...

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PMID: 20593488
DOI: 10.1002/path.2724

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