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Relationship of Gene Expression and Chromosomal Abnormalities in Colorectal Cancer

15 Feb 2006

Abstract excerpt

Several studies have verified the existence of multiple chromosomal abnormalities in colon cancer. However, the relationships between DNA copy number and gene expression have not been adequately explored nor globally monitored during the progression of the disease. In this work, three types of array-generated data (expression, single nucleotide polymorphism, and comparative genomic hybridization) were collected...

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PMID: 16489013
DOI: 10.1158/0008-5472.can-05-2569

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