Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

HLA-B locus in Caucasian patients with carbamazepine hypersensitivity.

Pharmacogenomics - 1 Sept 2006

Alfirevic Ana, Jorgensen Andrea L, Williamson Paula R, Chadwick David W, Park B Kevin, Pirmohamed Munir

Abstract excerpt

BACKGROUND: A strong pharmacogenetic association has been reported in Chinese patients between human leukocyte antigen (HLA)-B*1502 and carbamazepine (CBZ)-induced Stevens-Johnson syndrome (SJS). METHODS: We have genotyped the HLA-B alleles in 56 Caucasian patients with varying severities of CBZ hypersensitivity and 43 controls on CBZ without adverse effects. RESULTS: None of our patients (including two with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Drug Hypersensitivity
Share to Carbamazepine
Share to HLA-B Antigens

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HLA-B15 Antigen

Share to HLA-B7 Antigen

Share to HLA-B8 Antigen

Share to HLA-DR3 Antigen

Share to Toxicogenetics

Source

Identifiers

PMID: 16981842
DOI: 10.2217/14622416.7.6.813

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

HLA-B locus in Caucasian patients with carbamazepine hypersensitivity.PMID 16981842Read ↗

HLA genotype and carbamazepine-induced cutaneous adverse drug reactions: a systematic review.Semantic proximity Read ↗

Association between carbamazepine-induced cutaneous adverse drug reactions and the HLA-B*1502 allele among patients in central China.Semantic proximity Read ↗

Association of HLA-B*1502 allele and carbamazepine-induced Stevens-Johnson syndrome among Indians.Semantic proximity Read ↗

Carbamazepine-induced severe cutaneous adverse reactions and HLA genotypes in Koreans.Semantic proximity Read ↗

Association between HLA-B*1502 allele and antiepileptic drug-induced cutaneous reactions in Han Chinese.Semantic proximity Read ↗

HLA alleles and hypersensitivity to carbamazepine: an updated systematic review with meta-analysis.Semantic proximity Read ↗

Association between HLA and Stevens-Johnson syndrome induced by carbamazepine in Southern Han Chinese: genetic markers besides B*1502?Semantic proximity Read ↗

Association between the HLA-B alleles and carbamazepine-induced SJS/TEN: A meta-analysis.Semantic proximity Read ↗

Carbamazepine, HLA-B*1502 and risk of Stevens-Johnson syndrome and toxic epidermal necrolysis: US FDA recommendations.Semantic proximity Read ↗

Association of HLA-B*1502 and *1511 allele with antiepileptic drug-induced Stevens-Johnson syndrome in central China.Semantic proximity Read ↗

Association between HLA-B*1502 allele and carbamazepine-induced severe cutaneous adverse reactions in Han people of southern China mainland.Semantic proximity Read ↗

HLA-B alleles associated with severe cutaneous reactions to antiepileptic drugs in Han Chinese.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.