Article
Impact of selectin gene polymorphisms on rapid progression to end-stage renal disease in patients with IgA nephropathy.
Internal medicine (Tokyo, Japan) - 1 Jan 2006
Watanabe Yusuke, Inoue Tsutomu, Okada Hirokazu, Kotaki Shuhei, Kanno Yoshihiko, Kikuta Tomohiro, Suzuki Hiromichi
Abstract excerpt
OBJECTIVE: It is evident that leukocyte infiltration plays an important role in the pathogenesis of IgA nephropathy (IgAN). Selectin is one of the key adhesion molecules involved in leukocyte infiltration. Recent studies demonstrated a significant association between the selectin gene polymorphis...
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