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Article

Functional impact of IgA nephropathy-associated selectin gene haplotype on leukocyte-endothelial interaction.

Immunogenetics - 1 Jun 2006

Takei Takashi, Hiraoka Megumi, Nitta Kosaku, Uchida Keiko, Deushi Michiyo, Yu Tao, Nitta Noriko, Tsuchiya Ken, Yumura Wako, Nihei Hiroshi, Nakamura Yusuke, Yoshida Masayuki

Abstract excerpt

Previously, we discovered single-nucleotide polymorphisms (SNPs) associated with Immunoglobulin A (IgA) nephropathy in selectin genes, which were 712C>T(P238S) in L selectin, -642A>G in the promoter region of L selectin, and 1402C>T(H468Y) in E selectin. Interestingly, these SNPs were in nearly complete linkage disequilibrium, thus two haplotypes, disease-associated TGT and wild-type (Wt) CAC, were constructed....

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Identifiers

PMID: 16738933
DOI: 10.1007/s00251-006-0120-7

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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