Article
The E-selectin gene polymorphism and carotid atherosclerosis in end-stage renal disease.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association - 1 Jul 2006
Testa Alessandra, Benedetto Francesco A, Spoto Belinda, Pisano Anna, Tripepi Giovanni, Mallamaci Francesca, Malatino Lorenzo S, Zoccali Carmine
Abstract excerpt
BACKGROUND: E-selectin is a cell surface glycoprotein that mediates the adhesion of leucocytes to vessels endothelium, an important early step in the atherosclerotic process. End-stage renal disease (ESRD) is a highly atherogenic disease but it is unknown whether genetic polymorphism(s) in the E-selectin gene plays a role in the severity of arterial damage in this condition. Method. In this study, we tested...
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