Article
The association of Klotho polymorphism with disease progression and mortality in IgA nephropathy.
Kidney & blood pressure research - 1 Jan 2012
Ko Gang Jee, Lee Eun Ah, Jeon Un Sil, Pyo Heui Jung, Chin Ho Jun, Chae Dong Wan, Kim Suhnggwon, Kwon Young Joo
Abstract excerpt
BACKGROUNDS: IgA nephropathy (IgAN) is the most common primary glomerulonephritis causing end stage renal disease (ESRD), and vasculopathy is known to involve disease progression. Klotho, a gene related to aging, has been reported to play a role in atherosclerosis and endothelial dysfunction. We investigated whether klotho gene polymorphism affect clinical course of IgAN. METHODS: The data registered for PREMIER...
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