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Expression and functional features of NaCT, a sodium-coupled citrate transporter, in human and rat livers and cell lines

14 Sept 2006

Abstract excerpt

In this article, we report on the expression and function of a Na(+)-coupled transporter for citrate, NaCT, in human and rat liver cell lines and in primary hepatocytes from the rat liver. We also describe the polarized expression of this transporter in human and rat livers. Citrate uptake in human liver cell lines HepG2 and Huh-7 was obligatorily dependent on Na+. The uptake system showed a preference for...

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PMID: 16973915
DOI: 10.1152/ajpgi.00371.2006

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