Article
Auditory mechanotransduction in the absence of functional myosin-XVa.
The Journal of physiology - 1 Nov 2006
Stepanyan Ruben, Belyantseva Inna A, Griffith Andrew J, Friedman Thomas B, Frolenkov Gregory I
Abstract excerpt
In hair cells of all vertebrates, a mechanosensory bundle is formed by stereocilia with precisely graded heights. Unconventional myosin-XVa is critical for formation of this bundle because it transports whirlin and perhaps other molecular components responsible for programmed elongation of stereocilia to the stereocilia tips. A tip of a stereocilium is the site of stereocilia growth and one of the proposed sites...
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