Article
Identification of a filamin docking site on PTP-PEST.
The Journal of biological chemistry - 10 Nov 2006
Playford Martin P, Lyons Patrick D, Sastry Sarita K, Schaller Michael D
Abstract excerpt
PTP-PEST is a cytoplasmic protein-tyrosine phosphatase (PTP) implicated in the regulation of biological processes such as cell motility, cytokinesis, focal adhesion disassembly, and lymphocyte activation. Using a proteomics approach, filamin-A was identified as a novel interacting protein that bound to GST-PTP-PEST. This interaction was confirmed in vitro and in cells by coimmunoprecipitation. The site of filamin...
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