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Article

Pellino3 is a novel upstream regulator of p38 MAPK and activates CREB in a p38-dependent manner.

The Journal of biological chemistry - 29 Jul 2005

Butler Marion P, Hanly Jennifer A, Moynagh Paul N

Abstract excerpt

Engagement of the interleukin-1 (IL-1) and Toll-like receptors triggers mitogen-activated protein kinase (MAPK) pathways and activation of transcription factors such as NFkappaB and AP-1. Recent studies have identified members of the Pellino protein family as novel mediators in mediating activation of these pathways. However, no evidence has been presented to date to suggest a role for the Pellino proteins in...

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Identifiers

PMID: 15917247
DOI: 10.1074/jbc.M500756200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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