Article
Inhibition of hendra virus fusion.
Journal of virology - 1 Oct 2006
Porotto M, Doctor L, Carta P, Fornabaio M, Greengard O, Kellogg G E, Moscona A
Abstract excerpt
Hendra virus (HeV) is a recently identified paramyxovirus that is fatal in humans and could be used as an agent of bioterrorism. The HeV receptor-binding protein (G) is required in order for the fusion protein (F) to mediate fusion, and analysis of the triggering/activation of HeV F by G should lead to strategies for interfering with this key step in viral entry. HeV F, once triggered by the receptor-bound G, by...
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