Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of the functional KL-VS variant of Klotho gene with early-onset ischemic stroke.

Biochemical and biophysical research communications - 17 Dec 2010

Majumdar Vijaya, Nagaraja Dindagur, Christopher Rita

Abstract excerpt

Genetic variants of Klotho have been reported to be associated with human longevity and atherosclerotic vascular events and risk factors. However, very few studies have explored their association with ischemic stroke. We hypothesized that the functional KL-VS and the exonic C1818T variants of Klotho gene may be associated with ischemic stroke in Indian population. We enrolled a total of 460 patients with ischemic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Age of Onset
Share to Cardiovascular Diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Gene Frequency

Share to Glucuronidase

Share to Klotho Proteins

Share to Stroke

Share to Young Adult

Source

Identifiers

PMID: 21093413
DOI: 10.1016/j.bbrc.2010.11.045

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of the functional KL-VS variant of Klotho gene with early-onset ischemic stroke.PMID 21093413Read ↗

Klotho is a genetic risk factor for ischemic stroke caused by cardioembolism in Korean females.Semantic proximity Read ↗

A klotho gene single nucleotide polymorphism is associated with the onset of stroke and plasma klotho concentrationSemantic proximity Read ↗

Association between a functional variant of the KLOTHO gene and high-density lipoprotein cholesterol, blood pressure, stroke, and longevity.Semantic proximity Read ↗

Absence of kl-vs variant of klotho gene in Iranian cardiac patients (comparison to the world populations).Semantic proximity Read ↗

Association of exonic variants of Klotho with metabolic syndrome in Asian Indians.Semantic proximity Read ↗

The KL-VS polymorphism of KLOTHO gene is protective against retinopathy incidence in patients with type 1 diabetes.Semantic proximity Read ↗

The differential effects of age on the association of KLOTHO gene polymorphisms with coronary artery disease.Semantic proximity Read ↗

Circulating Klotho Is Higher in Cerebrospinal Fluid than Serum and Elevated Among KLOTHO Heterozygotes in a Cohort with Risk for Alzheimer’s DiseaseSemantic proximity Read ↗

Association of Klotho polymorphisms with healthy aging: a systematic review and meta-analysis.Semantic proximity Read ↗

The functional "KL-VS" variant of KLOTHO is not associated with type 2 diabetes in 5028 UK Caucasians.Semantic proximity Read ↗

The frequency of Klotho KL-VS polymorphism in a large Italian population, from young subjects to centenarians, suggests the presence of specific time windows for its effect.Semantic proximity Read ↗

Longevity Klotho gene polymorphism and the risk of dementia in older men.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.