Article
KLOTHO gene polymorphism is associated with coronary artery stenosis but not with coronary calcification in a Korean population.
International heart journal - 1 Jan 2009
Jo Sang-Ho, Kim Seong-Gyun, Choi Young Jin, Joo Na-Rae, Cho Goo-Yeong, Choi Sun-Ryoung, Kim Eun-Jung, Kim Hyun-Sook, Kim Hyung-Jik, Rhim Chong-Yun
Abstract excerpt
Experimental studies have demonstrated KLOTHO gene polymorphism might be associated with vascular atherosclerosis and calcification. However, the impact of this genetic variant on human coronary arteries still remains to be elucidated. We investigated the effect of a KLOTHO gene variant on coronary artery stenosis and calcification. Four hundred and thirty-four patients referred for chest pain were enrolled. All...
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