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Article

Mutations in laminin alpha 1 result in complex, lens-independent ocular phenotypes in zebrafish.

Developmental biology - 1 Nov 2006

Semina Elena V, Bosenko Dmitry V, Zinkevich Natalya C, Soules Kelly A, Hyde David R, Vihtelic Thomas S, Willer Gregory B, Gregg Ronald G, Link Brian A

Abstract excerpt

We report phenotypic and genetic analyses of a recessive, larval lethal zebrafish mutant, bal(a69), characterized by severe eye defects and shortened body axis. The bal(a69) mutation was mapped to chromosome 24 near the laminin alpha 1 (lama1) gene. We analyzed the lama1 gene sequence within bal(a69) embryos and two allelic mutants, bal(arl) and bal(uw1). Missense (bal(a69)), nonsense (bal(arl)), and frameshift...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 16973147
DOI: 10.1016/j.ydbio.2006.07.005

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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