Genetic analysis of laminin A reveals diverse functions during morphogenesis in Drosophila.

doi:10.1242/dev.118.2.325

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Article

Genetic analysis of laminin A reveals diverse functions during morphogenesis in Drosophila.

Development (Cambridge, England) - 1 Jun 1993

Henchcliffe C, García-Alonso L, Tang J, Goodman C S

Abstract excerpt

In order to dissect the functions of laminin A in vivo, we have undertaken a molecular and genetic characterization of the laminin A subunit (lamA) gene in Drosophila. Sequence analysis predicts a multidomain structure similar to mammalian homologs. We generated a series of complete and partial l...

Topics

Animals
Base Sequence
Drosophila
Extremities
Eye
Humans
Laminin
Mice
Microscopy, Electron, Scanning
Molecular Sequence Data
Morphogenesis
Mutagenesis, Insertional
Open Reading Frames
Phenotype
Sequence Homology, Amino Acid
Wings, Animal

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