Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Laminin beta1 and gamma1 containing laminins are essential for basement membrane integrity in the zebrafish eye.

Investigative ophthalmology & visual science - 1 Jun 2007

Lee Jiwoon, Gross Jeffrey M

Abstract excerpt

PURPOSE: In this study recessive zebrafish mutations in the genes encoding laminin beta1 (lamb1) and laminin gamma1 (lamc1) were used to determine the functions of these laminin proteins during ocular basement membrane formation and during zebrafish eye development. METHODS: Ocular defects in lamb1 and lamc1 mutants were characterized by using a combination of histology, immunohistochemistry, in situ...

Topics

Animals
Basement Membrane
Cell Differentiation
Embryo, Nonmammalian
Immunohistochemistry
In Situ Hybridization
Laminin
Lens Capsule, Crystalline
Microscopy, Electron
Mutation
RNA, Messenger

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Retina

Zebrafish

Zebrafish Proteins

Source

Identifiers

PMID: 17525174
DOI: 10.1167/iovs.06-1211

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Laminin beta1 and gamma1 containing laminins are essential for basement membrane integrity in the zebrafish eye.PMID 17525174Read ↗

laminin alpha 1 gene is essential for normal lens development in zebrafish.Semantic proximity Read ↗

Lens extrusion from Laminin alpha 1 mutant zebrafish.Semantic proximity Read ↗

Regulation of Adult Zebrafish Retinal Regeneration by Lamβ1b-Chain-Containing LamininsSemantic proximity Read ↗

Defective formation of the inner limiting membrane in laminin beta2- and gamma3-null mice produces retinal dysplasia.Semantic proximity Read ↗

Drosophila laminins act as key regulators of basement membrane assembly and morphogenesis.Semantic proximity Read ↗

Laminin alpha subunits and their role in C. elegans development.Semantic proximity Read ↗

Form and function: The laminin family of heterotrimersSemantic proximity Read ↗

Laminins and their roles in mammalsSemantic proximity Read ↗

Impaired retinal differentiation and maintenance in zebrafish laminin mutants.Semantic proximity Read ↗

The role of the laminin beta subunit in laminin heterotrimer assembly and basement membrane function and development in C. elegans.Semantic proximity Read ↗

Mutations in laminin alpha 1 result in complex, lens-independent ocular phenotypes in zebrafish.Semantic proximity Read ↗

Characterization of the laminin gene family and evolution in zebrafishSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.