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Article

Impaired retinal differentiation and maintenance in zebrafish laminin mutants.

Investigative ophthalmology & visual science - 1 Jun 2007

Biehlmaier Oliver, Makhankov Yuri, Neuhauss Stephan C F

Abstract excerpt

PURPOSE: To characterize morphologic and physiological alterations in the retina of three laminin mutant zebrafish, bashful (bal, lama1), grumpy (gup, lamb1), and sleepy (sly, lamc1), which were identified in forward genetic screens and were found to be impaired in visual functions. METHODS: Mutant larvae were observed for defects in visual behavior by testing their optokinetic response (OKR). In addition,...

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PMID: 17525225
DOI: 10.1167/iovs.06-1212

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ERG

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