Article
Essential and overlapping roles for laminin alpha chains in notochord and blood vessel formation.
Developmental biology - 1 Jan 2006
Pollard Steven M, Parsons Michael J, Kamei Makoto, Kettleborough Ross N W, Thomas Kevin A, Pham Van N, Bae Moon-Kyoung, Scott Annabelle, Weinstein Brant M, Stemple Derek L
Abstract excerpt
Laminins are major constituents of basement membranes and have wide ranging functions during development and in the adult. They are a family of heterotrimeric molecules created through association of an alpha, beta and gamma chain. We previously reported that two zebrafish loci, grumpy (gup) and sleepy (sly), encode laminin beta1 and gamma1, which are important both for notochord differentiation and for proper...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
