Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

LET-711, the Caenorhabditis elegans NOT1 ortholog, is required for spindle positioning and regulation of microtubule length in embryos.

Molecular biology of the cell - 1 Nov 2006

DeBella Leah R, Hayashi Adam, Rose Lesilee S

Abstract excerpt

Spindle positioning is essential for the segregation of cell fate determinants during asymmetric division, as well as for proper cellular arrangements during development. In Caenorhabditis elegans embryos, spindle positioning depends on interactions between the astral microtubules and the cell cortex. Here we show that let-711 is required for spindle positioning in the early embryo. Strong loss of let-711...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aurora Kinase A
Share to Caenorhabditis elegans Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Centrosome

Share to Embryo, Nonmammalian

Share to Microtubules

Share to Sequence Homology

Share to Spindle Apparatus

Share to Tubulin

Source

Open in PubMed Open full text

Identifiers

PMID: 16971515
DOI: 10.1091/mbc.e06-02-0107
PMCID: PMC1635396

Genes

CCR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

LET-711, the Caenorhabditis elegans NOT1 ortholog, is required for spindle positioning and regulation of microtubule length in embryos.PMID 16971515Read ↗

ZYG-9, TAC-1 and ZYG-8 together ensure correct microtubule function throughout the cell cycle of C. elegans embryos.Semantic proximity Read ↗

ZYG-9, a Caenorhabditis elegans protein required for microtubule organization and function, is a component of meiotic and mitotic spindle poles.Semantic proximity Read ↗

The let-99 gene is required for proper spindle orientation during cleavage of the C. elegans embryo.Semantic proximity Read ↗

Dissection of cell division processes in the one cell stage Caenorhabditis elegans embryo by mutational analysis.Semantic proximity Read ↗

The C. elegans zyg-1 gene encodes a regulator of centrosome duplication with distinct maternal and paternal roles in the embryo.Semantic proximity Read ↗

Microtubule stiffening by the doublecortin-domain protein ZYG-8 contributes to mitotic spindle orientation during zygote division in Caenorhabditis elegans.Semantic proximity Read ↗

C. elegans homologue of the Caf1 gene, which encodes a subunit of the CCR4-NOT complex, is essential for embryonic and larval development and for meiotic progressionSemantic proximity Read ↗

Microtubule stiffening by the doublecortin-domain protein ZYG-8 contributes to mitotic spindle orientation during zygote division in <i>Caenorhabditis elegans</i>Semantic proximity Read ↗

Molecular analysis of zyg-11, a maternal-effect gene required for early embryogenesis of Caenorhabditis elegans.Semantic proximity Read ↗

Cell polarity-dependent centrosome separation in the C. elegans embryo.Semantic proximity Read ↗

The kinetically dominant assembly pathway for centrosomal asters in Caenorhabditis elegans is gamma-tubulin dependent.Semantic proximity Read ↗

The spatiotemporal distribution of LIN-5/NuMA regulates spindle orientation and tissue organization in the <i>C. elegans</i> germ lineSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.