Article
Influence of RNA synthesis on DNA-repair replication in human cell extracts.
Mutation research - 1 Aug 1990
Frosina G, Wood R D
Abstract excerpt
An in vitro system allowing human cell extracts to carry out excision repair in ultraviolet light-irradiated, closed circular DNA was used to study the influence of transcription on repair synthesis. RNA synthesis from plasmid DNA containing bacterial transcription units was obtained by addition of Escherichia coli RNA polymerase and ribonucleoside triphosphates to the repair-incubation mixture. No increase in...
Topics
- Cell Extracts
- Cell Line
- DNA
- DNA Repair
- DNA Replication
- DNA-Directed RNA Polymerases
- Humans
- Mutation
- Plasmids
- RNA
- Transcription, Genetic
- Ultraviolet Rays