Article
Modulating the proteinase inhibitory profile of a plant cystatin by single mutations at positively selected amino acid sites.
The Plant journal : for cell and molecular biology - 1 Nov 2006
Kiggundu Andrew, Goulet Marie-Claire, Goulet Charles, Dubuc Jean-François, Rivard Daniel, Benchabane Meriem, Pépin Geneviève, van der Vyver Christell, Kunert Karl, Michaud Dominique
Abstract excerpt
Cysteine proteinase inhibitors of the cystatin superfamily have several important functions in plants, including the inhibition of exogenous cysteine proteinases during herbivory or infection. Here we used a maximum-likelihood approach to assess whether plant cystatins, like other proteins implicated in host-pest interactions, have been subject to positive selection during the course of their evolution. Several...
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