Article
A study of PSORS1C1 gene polymorphisms in Chinese patients with psoriasis.
The British journal of dermatology - 1 Jul 2005
Chang Y T, Liu H N, Shiao Y M, Lin M W, Lee D D, Liu M-T, Wang W J, Wu S, Lai C Y, Tsai S F
Abstract excerpt
BACKGROUND: Although genetic analyses have identified the HLA-Cw*0602 allele as the major risk allele for chronic plaque psoriasis in various ethnic groups, it has been proposed that the association of Cw*0602 is due to linkage disequilibrium and that other nearby genes are involved in susceptibility to psoriasis. The psoriasis susceptibility 1 candidate 1 (PSORS1C1, formerly SEEK1) gene, located 127 kb telomeric...
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