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Article

Frustration and hydrophobicity interplay in protein folding and protein evolution.

The Journal of chemical physics - 28 Aug 2006

Oliveira Leandro C, Silva Ricardo T H, Leite Vitor B P, Chahine Jorge

Abstract excerpt

A lattice model is used to study mutations and compacting effects on protein folding rates and folding temperature. In the context of protein evolution, we address the question regarding the best scenario for a polypeptide chain to fold: either a fast nonspecific collapse followed by a slow rearrangement to form the native structure or a specific collapse from the unfolded state with the simultaneous formation of...

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Source

Identifiers

PMID: 16965054
DOI: 10.1063/1.2335638

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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