Roles of mutation and recombination in the evolution of protein thermodynamics.

Abstract excerpt

We present a comprehensive study of the evolutionary origin of the thermodynamic behavior of proteins. With the use of a simplified model, we exhaustively enumerate the space of all sequences and the space of all structures, simulate the evolutionary relationship between sequences and structures, and characterize the steady-state sequence distribution for all structures in terms of several thermodynamic...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Evolution, Molecular
• Share to Mutation
• Share to Proteins