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Seven naturally variant loci serve as genetic modifiers of <i> Lamc2 <sup>jeb</sup> </i> induced non-Herlitz Junctional Epidermolysis Bullosa in mice

2023-03-03

Abstract excerpt

Epidermolysis Bullosa (EB) is a group of rare genetic disorders that compromise the structural integrity of the skin such that blisters and subsequent erosions occur after minor trauma. While primary genetic risk of all subforms of EB adhere to Mendelian patterns of inheritance, their clinical presentations and severities can vary greatly, implying genetic modifiers. The Lamc2 jeb mouse model of non-Herlitz junc...

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Literature Corpus work
59618b27-43d1-5123-82f5-4f7a4120a59d
DOI
10.1101/2023.03.03.530930
Open publication

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Seven naturally variant loci serve as genetic modifiers of <i> Lamc2 <sup>jeb</sup> </i> induced non-Herlitz Junctional Epidermolysis Bullosa in miceDOI 10.1101/2023.03.03.530930
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