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Article

Role of alternative oxidase gene in pathogenesis of Cryptococcus neoformans.

Infection and immunity - 1 Oct 2003

Akhter Shamima, McDade Henry C, Gorlach Jenifer M, Heinrich Garrett, Cox Gary M, Perfect John R

Abstract excerpt

We identified a homologue of the alternative oxidase gene in a screen to identify genes that are preferentially transcribed in response to a shift to 37 degrees C in the human-pathogenic yeast Cryptococcus neoformans. Alternative oxidases are nucleus-encoded mitochondrial proteins that have two putative roles: they can function in parallel with the classic cytochrome oxidative pathway to produce ATP, and they may...

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Identifiers

PMID: 14500501
DOI: 10.1128/IAI.71.10.5794-5802.2003
PMCID: PMC201089

Genes

AOX1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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