Article
The emerging role of GATA transcription factors in development and disease.
Expert reviews in molecular medicine - 8 Mar 2016
Lentjes Marjolein H F M, Niessen Hanneke E C, Akiyama Yoshimitsu, de Bruïne Adriaan P, Melotte Veerle, van Engeland Manon
Abstract excerpt
The GATA family of transcription factors consists of six proteins (GATA1-6) which are involved in a variety of physiological and pathological processes. GATA1/2/3 are required for differentiation of mesoderm and ectoderm-derived tissues, including the haematopoietic and central nervous system. GATA4/5/6 are implicated in development and differentiation of endoderm- and mesoderm-derived tissues such as induction...
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