Article
Targeting protein stability with a small molecule.
Cell - 8 Sept 2006
Lampson Michael A, Kapoor Tarun M
Abstract excerpt
Both genetic approaches and small-molecule inhibitors can be used to perturb protein function. Banaszynski et al. (2006) now describe a strategy to regulate the stability of a target protein, in which specificity is provided by a genetically encoded tag and temporal control is imparted by a small molecule.
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