Article
Chemical inducers of targeted protein degradation.
The Journal of biological chemistry - 9 Apr 2010
Raina Kanak, Crews Craig M
Abstract excerpt
The functions of many cellular proteins have been elucidated by selective gene inactivation and subsequent phenotypic analysis. For example, genetic mutations, gene knock-out generation, and the use of RNA interference to target mRNA for degradation can all result in decreased production of a spe...
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