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Article

Developmental competence of human in vitro aged oocytes as host cells for nuclear transfer

6 Sept 2006

Abstract excerpt

BACKGROUND: Improving human nuclear transfer (NT) efficiencies is paramount for the development of patient-specific stem cell lines, although the opportunities remain limited owing to difficulties in obtaining fresh mature oocytes. METHODS: Therefore, the developmental competence of aged, failed-to-fertilize human oocytes as an alternate cytoplasmic source for NT was assessed and compared with use of fresh,...

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PMID: 16957049
DOI: 10.1093/humrep/del345

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