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Article

Assessment of the developmental competence of human somatic cell nuclear transfer embryos by oocyte morphology classification

4 Dec 2008

Abstract excerpt

BACKGROUND: The oocyte plays a key role in reprogramming the epigenetic status of donor cell nuclei, and the absence of reprogramming elements in the cytoplasm or aberrant accumulation of proteins can trigger the abnormal development of nuclear transfer (NT) embryos. Previous studies have demonstrated the relationship between oocyte morphology and both embryo development and pregnancy outcome. In the present...

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PMID: 19073617
DOI: 10.1093/humrep/den407

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